Common Antibacterial Agent Contributes to Antibiotic Resistance

Common Antibacterial Agent Contributes to Antibiotic Resistance Common Antibacterial Agent Contributes to Antibiotic Resistance Stores are stocked with items promising to kill bacteria and many consumers purchase those products in an attempt to protect themselves from...

Jackson is our Valentine

Jackson is our Valentine Jackson is our Valentine February 14th is all about love and we sure do love our town of Jackson, Michigan. In fact, on this day 126 years ago, Jackson officially became a city. And did you know that the rose is the official flower of Jackson,...

IACUC Approves Intratracheal Administration

IACUC Approves Intratracheal Administration IACUC Approves Intratracheal Administration TransPharm’s Institutional Animal Care and Use Committee (IACUC) recently approved intratracheal (IT) administration as a new route of inoculating and dosing mice. Intratracheal...

A “Two-Hit” Model of Sepsis

A “Two-Hit” Model of Sepsis A “Two-Hit” Model of Sepsis TransPharm recently validated a “two-hit” model of sepsis in which mice undergo cecal ligation and puncture (CLP) followed by intranasal instillation with bacteria to initiate...

Cease and Persist?

Cease and Persist? Cease and Persist? After a bacterial infection is established, a small percentage of the bacteria slow their metabolism in response to environmental stressors. This semi-dormant state affords increased tolerance to antibiotics, especially...

Biofilms: Skimming the Surface

Biofilms: Skimming the Surface Biofilms: Skimming the Surface There are two basic forms of microbes: free-floating and anchored. While free-floating microbes are better understood, 90% of all microorganisms are anchored. Anchored microbes have the ability to form...