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Fall 2017 Newsletter

A Note from the President

The year is coming to a close and 2018 is right around the corner. It’s hard to believe, but January will mark TransPharm’s 10-year anniversary. Our company started with just three employees, but ten years later we have quadrupled in size. The total revenue our first year was $147k; now we do over $2 million annually. Time flies when you’re having fun! To celebrate our landmark anniversary and as a thank you to our clients, we are offering 10% off all studies booked by December 21st. See below for more details.

Also, we’d like to remind you that TransPharm will be closed starting Monday, December 25th and will reopen on Tuesday, January 2nd. The last day for animal deliveries is December 18th, with studies ending on the 22nd. Studies for early January (and any that you wish to be 10% off!) should be booked by December 21st. We will be checking email periodically, and this is the best way to reach us during our break. We wish you and yours a joyous holiday season and a happy new year.

Daniel Ross
President & CEO


10% Off ALL Studies!

Celebrate our 10-year anniversary with 10% off! All studies booked* by 12/21/2017 are eligible for the discount. Contact Marci for a quote today!

*Signed quotes and a purchase order must be received by end of business on Thursday, December 21, 2017.


In the Lab

TransPharm has added a new animal model of induced chronic osteomyelitis (bone infection). Osteomyelitis results in pain, loss of mobility, and significant morbidity. Current treatment requires prolonged antibiotic therapy and surgical debridement of sequestra (dead bone). Due to poor drug penetration into the bone and an increase in antibiotic-resistant bacteria, there is an urgent need for novel therapeutics. Our model serves as a screening tool to identify which antimicrobials are most clinically efficacious.

Animals are challenged via injection into the cancellous bone marrow through the anterior surface of the proximal tibia (see photo). The infection is allowed to incubate for up to 4 weeks before the tibia is harvested for CFU enumeration. The induced chronic osteomyelitis model is currently available for S. aureus and S. epidermidis infections in Sprague-Dawley rats. Additional validations are available upon request.

Santiago R. Lopez, Ph.D.
Chief Scientific Officer


Our Research Process

Interested in learning more about what we do here at TransPharm? This infographic walks you through each step of our research process. As in vivo experts of infectious disease, we are happy to provide a professional consultation to help identify your needs. Our flexible study design means all studies can be customized – you choose your animal strain, pathogen, infection route, treatment, endpoints, and more. Additional validations are available upon request. Contact us today for more information!


Community Involvement

The Brooklyn-Irish Hills Chamber of Commerce hosted their annual Career and College Expo in mid-October. Chief Scientific Officer, Dr. Santiago Lopez, and Associate Scientist, Jeremy Covell, manned the TransPharm booth and had the opportunity to speak with local high school students about scholarship opportunities and our summer internship program. Further, our President and CEO, Dan Ross, was invited to speak to over 800 students, faculty, and staff on the meaning of success in business. We are lucky to have so many events which allow us to stay actively involved in our community.


A Field Trip to TransPharm

Students from Madison High School in Adrian, MI visited TransPharm in early November to gain hands-on laboratory experience. Following a tour of our facility, Dr. Santiago Lopez and teacher Katie McGormley instructed a laboratory activity titled, “Transduction of an antibiotic-resistance gene in E. coli cells.” This experiment introduced the concepts of bacteriophages, horizontal gene transfer, and mutations. The students enjoyed their time in the lab and were excited to see antibiotic-resistant colony growth on their agar plates the following day.

 

 

 

 

 

 

 

 


The Big 400 Tour

Our team had a great time on The Big 400 Tour in October. The Big 400 promotes the economic development, use, and preservation of a 20 mile by 20 mile area in southern central Michigan. We enjoyed visiting local attractions and businesses including a state park, a sustainable farm, an ice cream shop, and the oldest continuously operating cider mill in Michigan. Below is our group photo in front of Mill Creek, the largest tributary of the Huron River.